Publications: (*equal contributions)



Taylor MR*, Martin EA*, Sinnen B, Trilokekar R, Ranza E, Antonarakis SE, Williams ME. Kirrel3-mediated synapse formation is attenuated by disease-associated missense variants. J. of Neuroscience 2020 (in press)


Das S, Chen D, Callor WB, Christensen E, Coon H*, Williams ME*. DiI-mediated analysis of presynaptic and postsynaptic structures in human post-mortem brain tissue. J. Comp. Neurology 2019 (in press).



Basu R, Duan X, Taylor MR, Martin A, Muralidhar S, Wang Y, Gangi-Wellman L, Das SC, Yamagata M, West PJ, Sanes JR, Williams ME. Heterophilic Type II cadherins are required for high magnitude synaptic potentiation in the hippocampus. Neuron. 2017 Sept 27. PMCID: PMC5634529



Martin EA, Woodruff D, Rawson R, and Williams ME. Examining hippocampal mossy fiber synapses by 3D electron microscopy in wildtype and Kirrel3 knockout mice. eNeuro. 2017 May-Jun;4(3) PubMed PMID: 28670619; PubMed Central PMCID: PMC5490256..



Rawson R, Martin EA, and Williams ME. Mechanisms of input and output synaptic specificity:  Finding partners, building synapses, and fine-tuning communication. Current Opinion in  Neurobiology. Curr Opin Neurobiol. 2017 Apr 4;45:39-44. PMID: 28388510



Martin EA*, Muralidhar S*, Wang Z, Cervantes DC, Basu R, Taylor MR, Hunter J, Cutforth T, Wilke SA, Ghosh A and Williams ME. The intellectual disability gene Kirrel3 regulates target-specific mossy fiber synapse development in the hippocampus. eLife 2015;4:e09395



Basu R, Taylor M, and Williams ME. The classic cadherins in synaptic specificity. Cell Adhesion and Migration. 2015,9(3):193-201. doi: 10.1080/19336918.2014.1000072.



Viswanathan S, Williams ME, Bloss EB, Stasevich TJ, Speer CM, Nern A, Pfeiffer BD, Hooks BM, Li WP, English BP, Tian T, Henry GL, Macklin JJ, Patel R, Gerfen CR, Zhuang X, Wang Y, Rubin GM, Looger LL. High-performance probes for light and electron microscopy. Nature Methods. 2015. Jun;12(6):568-76. doi: 10.1038/nmeth.3365.



Wilke SA, Hall BJ, Antonios J, DeNardo L, Otto S, Yuan B, Chen F, Robbins EM, Tiglio K, Williams ME, Qiu Z, Biederer T, and Ghosh A. NeuroD2 Regulates Development of Hippocampal Mossy Fiber Synapses. Neural Development 2012, 7:9



Williams ME, Wilke SA, Daggett A, Davis E, Otto S, Ripley B, Bushong EA, Ellisman M, Klein G, and Ghosh A.  Cadherin-9 regulates input-specific synaptic differentiation in the developing hippocampus. 2011 Neuron 71:640-655



Ripley B*, Otto S*, Tiglio K, Williams ME, and Ghosh A. Regulation of synaptic stability by AMPA receptor reverse signaling. 2011 PNAS 108(1):367-72



Williams ME, DeWit J, and Ghosh A.  Molecular mechanisms of synaptic specificity in developing neural circuits. 2010 Neuron 68(1);9-18



Williams ME*, Lu X*, McKenna WL*, Washington R, Boyette A, Strickland P, Dillon A, Kaprielian Z, Tessier-Lavigne M, Hinck L.  UNC5A promotes neuronal apoptosis during spinal cord development independent of netrin-1.  2006 Nature Neuroscience 9(8):996-8.



Williams ME*, Wu S*, McKenna W*, and Hinck L.  Surface expression of the netrin receptor UNC5H1 is regulated by a PICK1/PKC dependent mechanism.  2003 J. Neuroscience. 23:11279-88



Williams ME, Strickland P, Watanabe K, and Hinck L. UNC5H1 induces apoptosis via its juxtamembrane region through an interaction with NRAGE.  2003 J. Biol. Chem. 278:17483-90